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RQ-00203078, MedChemExpress
Beskrivning
RQ-00203078 is a highly selective, potent and orally active TRPM8 antagonist with IC50s of 5.3 nM and 8.3 nM for rat and human TRPM8 channels, respectively. RQ-00203078 shows little inhibitory action against TRPV1, TRPA1, TRPV4, or TRPM2 channels.
Specifikationer
Specifikationer
| Kemiskt namn eller material | RQ-00203078 |
| CAS | 1254205-52-1 |
| Färg | White |
| Anteckningar om renhetsgrad | Research |
| Molekylformel | C21H13ClF6N2O5S |
| Kvantitet | 5 mg |
| Löslighetsinformation | DMSO : ≥ 38 mg/mL (68.49 mM) |
| LEDER | O=C(O)C1=CC=C(S(=O)(N(C2=NC=C(C(F)(F)F)C=C2Cl)CC3=CC=C(OC(F)(F)F)C=C3)=O)C=C1 |
| Molekylvikt (g/mol) | 554.85 |
| Formel vikt | 554.85 |
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Research purposes only
Produkttitel
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