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RRM2B/p53R2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 18005-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16828034

  • 3313.85 SEK / 150µL
Estimated Shipment: 02-12-2021

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Description

Description

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and -gamma-irradiation that cause DNA damages. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression. p53R2 is an important target of p53 for tumor suppression.
Specifications

Specifications

RRM2B/p53R2
0.3 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q6PEE3, Q7LG56
p53R2, RRM2B
Rabbit
IgG
150 μL
-20°C
Primary
299976, 382985, 50484
Western Blot
Unconjugated
RRM2B
Liquid
Rrm2b
RRM2B,p53R2 Fusion Protein Ag12499
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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