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Invitrogen™ RSK3 Polyclonal Antibody

Beskrivning
Recommended positive controls: A431, HepG2, mouse brain, DDDDK-tagged RPS6KA2-transfected 293T. Predicted reactivity: Mouse (95%), Rat (96%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
RPS6KA2 (RSK3) serine/threonine kinase is a member of the ribosomal S6 kinase (RSK) family. It is believed that RPS6KA2 is a signal-transducing intermediate in the cellular response to several growth factors. It is found in many tissues, but in higher levels in lung and skeletal muscle. The p90 ribosomal S6 kinases (RSK)1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits and may have a tonic regulation on G-protein coupled signaling.
Specifikationer
Specifikationer
| Antigen | RSK3 |
| Användningsområden | Western Blot |
| Klassificering | Polyclonal |
| Koncentration | 1 mg/mL |
| Konjugera | Unconjugated |
| Formulering | 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 |
| Gen | RPS6KA2 |
| Genaccessionsnr. | Q15349, Q9WUT3 |
| Gene Alias | 90 kDa ribosomal protein S6 kinase 2; 90kDa; D17Wsu134e; HU-2; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1C; MAPKAPK1C; MAPKAPK-1c; mitogen-activated protein kinase-activated protein kinase 1C; p90rsk; p90-RSK 2; p90RSK2; p90-RSK3; pp90rsk; pp90RSK3; Protein-tyrosine kinase Mpk-9; ribosomal protein S6 kinase A2; ribosomal protein S6 kinase alpha 2; ribosomal protein S6 kinase alpha-2; ribosomal protein S6 kinase polypeptide 2; ribosomal protein S6 kinase, 90kD, polypeptide 2; ribosomal protein S6 kinase, 90kDa, polypeptide 2; ribosomal protein S6 kinase, polypeptide 2; ribosomal S6 kinase 3; Rps6ka2; Rps6ka-rs1; RSK; Rsk3; RSK-3; S6K-alpha; S6K-alpha 2; S6K-alpha2; S6K-alpha-2 |
| Gensymboler | RPS6KA2 |
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Produkttitel
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