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S1P1 Recombinant Rabbit Monoclonal Antibody (4F2), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand: Thermo Scientific MA538397

Product Code. 17227273

5730.00 SEK / 100µL

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Description

This antibody has been tested in direct-ELISA

S1P1 is a G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that is coupled to the G(i) subclass of heteromeric G proteins. S1P1 signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. It plays an important role in cell migration via its role in the reorganization of the actin cytoskeleton and formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. S1P1 is required for normal chemotaxis toward sphingosine 1-phosphate, normal embryonic heart development, and normal cardiac morphogenesis.

Specifications

Antigen	S1P1
Classification	Recombinant Monoclonal
Concentration	0.44 mg/mL
Formulation	PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.	P21453
Gene Symbols	S1PR1
Immunogen	A synthesized peptide derived from human EDG1
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Human
Product Type	Antibody
Isotype	IgG

Applications	Western Blot
Clone	4F2
Conjugate	Unconjugated
Gene	S1PR1
Gene Alias	AI849002; CD antigen CD363; CD363; CD363 antigen; CHEDG1; D1S3362; ECGF1; EDG1; EDG-1; EDG1 (Edg1); Edg1; rhodopsin family G protein-coupled receptor; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation sphingolipid G-protein-coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; etID43307.22; Lpb1; Lysophospholipid receptor B1; S1p; S1P receptor 1; S1P receptor Edg-1; s1p1; S1PR1; sphingosine 1-phosphate receptor; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor EDG1; Sphingosine 1-phosphate receptor Edg-1; sphingosine-1-phosphate receptor 1; wu:fb98f05
Host Species	Rabbit
Purification Method	Affinity chromatography
Regulatory Status	RUO
Gene ID (Entrez)	1901
Content And Storage	-20°C or -80°C if preferred
Form	Liquid

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S1P1 Recombinant Rabbit Monoclonal Antibody (4F2), Invitrogen™ > 100 μL; Unconjugated

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S1P1 Recombinant Rabbit Monoclonal Antibody (4F2), Invitrogen™

Description

Specifications

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