missing translation for 'onlineSavingsMsg'
Läs mer
  1. Home
  2. Products
  3. Proteinanalysreagenser
  4. Bioaktiva små molekyler
  5. STEMCELL Technologies SAHA

STEMCELL Technologies SAHA

Produktkod. 17110292
Encompass_Preferred
Change view
Klicka för att se tillgängliga alternativ
Kvantitet:
100 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Produktkod. Kvantitet
17110292 100 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Denna artikel kan inte returneras. Se returpolicy
Produktkod. 17110292 Leverantör STEMCELL Technologies Leverantörsnummer 73902

Please to purchase this item. Need a web account? Register with us today!

Denna artikel kan inte returneras. Se returpolicy

Beskrivning

Epigenetic modifier; Inhibits HDAC1 and HDAC3

  • SAHA (suberoylanilide hydroxamic acid) is a potent inhibitor of class I and class II histone deacetylases (HDACs)
  • This compound inhibits the activities of HDAC1 and HDAC3 (IC50 = 10 nM and 20 nM, respectively; Richon et al.) SAHA exhibits antiproliferative properties and can cause cell cycle arrest at G1 (Marks & Breslow)
  • Improves reprogramming efficiency from human and mouse somatic to induced pluripotent stem cells (Huangfu et al.)
  • Downregulates homologous recombination and leads to apoptosis in ovarian cancer cells when used in combination with olaparib (Konstantinopoulos et al.)
  • SAHA downregulates Nanog expression, which leads to proliferation inhibition in head and neck cancer stem cells (Kumar et al.)

Specifikationer

CAS 149647-78-9
Synonym Suberoylanilide hydroxamic acid; Vorinostat
Kvantitet 100 mg
Molekylformel C14H20N
Renhet ≥98%
Produkttitel
Välj ett problem

Genom att klicka på Skicka bekräftar du att du kan bli kontaktad av Fisher Scientific angående feedbacken du har lämnat i detta formulär. Vi kommer inte att dela din information för andra ändamål. All kontaktinformation som tillhandahålls ska också underhållas i enlighet med vår Sekretesspolicy.