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  5. Tocris Bioscience™ Santacruzamate A

Tocris Bioscience™ Santacruzamate A
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Produktkod. 18737006
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Produktkod. Kvantitet
18737006 10 mg
18757166 50 mg
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Produktkod. 18737006 Leverantör Tocris Bioscience™ Leverantörsnummer 7191/10

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Beskrivning

Highly potent and selective HDAC2 inhibitor

Santacruzamate A is a highly potent and selective histone deactylase 2 (HDAC2) inhibitor (IC50 = 112 - 119 pM). Also inhibits HDAC6 in nanomolar range (IC50 = 433 nM). Displays >3500 fold selectivity for HDAC2 over HDAC6, and >8500-fold selectivity over HDAC4 (IC50 >1 μM for HDAC4). Inhibits growth of HuT-78 cutaneous T-cell lymphoma cell line. Identified as targeting human host proteins that interact with SARS-CoV-2.
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Specifications

Kemiskt namn eller material Ethyl N-[4-oxo-4-[(2-phenylethyl)amino]butyl]carbamate
CAS 1477949-42-0
Kvantitet 10 mg
Mål Class II Histone Deacetylases Inhibitors
Molekylformel C15H22N2O3
Renhet 0.98
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