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ACROBiosystems SARS-CoV-2 (COVID-19) S protein RBD (N354D), His Tag

POA

Specifications

Accession Number QHD43416.1 (N354D)
Molecular Weight (g/mol) 27.0 kDa
Source SARS-CoV-2 S protein RBD (N354D), His Tag (SPD-S52H5) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Phe 541 (Accession # QHD43416.1 (N354D)).
Immunogen Arg 319 - Phe 541
Storage Requirements -20°C
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Description

Description

It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.0 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

QHD43416.1 (N354D)
SARS-CoV-2 S protein RBD (N354D), His Tag (SPD-S52H5) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Phe 541 (Accession # QHD43416.1 (N354D)).
-20°C
S protein RBD
SARS-CoV-2
PBS, pH7.4
HEK293
Viral Proteins
27.0 kDa
Arg 319 - Phe 541
Spike,S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD,COVID-19
Unconjugated
His Tag
Less than 1.0 EU / µg by the LAL method.
Powder
>95% as determined by SDS-PAGE
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