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ACROBiosystems SARS-CoV-2 (COVID-19) S protein RBD (N354D), His Tag
POA
Specifications
Accession Number | QHD43416.1 (N354D) |
---|---|
Molecular Weight (g/mol) | 27.0 kDa |
Source | SARS-CoV-2 S protein RBD (N354D), His Tag (SPD-S52H5) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Phe 541 (Accession # QHD43416.1 (N354D)). |
Immunogen | Arg 319 - Phe 541 |
Storage Requirements | -20°C |
Description
It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.0 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
QHD43416.1 (N354D) | |
SARS-CoV-2 S protein RBD (N354D), His Tag (SPD-S52H5) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Phe 541 (Accession # QHD43416.1 (N354D)). | |
-20°C | |
S protein RBD | |
SARS-CoV-2 | |
PBS, pH7.4 | |
HEK293 | |
Viral Proteins |
27.0 kDa | |
Arg 319 - Phe 541 | |
Spike,S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD,COVID-19 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / µg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |