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Invitrogen™ SARS-CoV-2 Spike Protein (RBD) Recombinant Rabbit Monoclonal Antibody (HL257)
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Produktkod. 17149425 Handla allt Thermo Scientific Produkter
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100 μL
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17149425 100 μL
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Produktkod. 17149425 Leverantör Invitrogen™ Leverantörsnummer MA536253

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Rabbit Recombinant Monoclonal Antibody

Positive control: 293T , SARS-CoV-2 spike (Full length)-transfected 293T , SARS-CoV-2 (2019-nCoV) Spike. Specificity: This antibody detects SARS-CoV-2 Spike protein, but does not cross-react with SARS-CoV or MERS-CoV spike proteins based on our internal testing.

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.
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Specifikationer

Antigen SARS-CoV-2 Spike Protein (RBD)
Användningsområden ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Klassificering Recombinant Monoclonal
Klona HL257
Koncentration 1 mg/mL
Konjugera Unconjugated
Formulering PBS with no preservative
Gene Alias Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
Värd art Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of SARS-CoV-2 Spike (S1) (SARS-CoV-2 (strain Wuhan-Hu-1)). The exact sequence is proprietary.
Reningsmetod Protein A
Kvantitet 100 μL
Regulatorisk status RUO
Primär eller sekundär Primary
Målarter Virus
Innehåll och lagring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Liquid
Isotyp IgG
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