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STEMCELL Technologies SB202190

p38 MAPK inhibitor

3187.35 SEK - 6164.10 SEK

Specifications

CAS 152121-30-7
Molecular Formula C20H14FN3O
Purity ≥98%
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
17100102
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STEMCELL Technologies
72632
10 mg
3187.35 SEK
10mg
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17110102
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STEMCELL Technologies
72634
25 mg
6164.10 SEK
25mg
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Estimated Shipment: 26-06-2024
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Description

Description

  • SB202190 is a selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38α (SAPK2A, MAPK14) and p38β (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively (Davies et al.; Jiang et al.) As a pyridinyl imidazole inhibitor, SB202190 directly binds p38 MAP kinases in the ATP binding pocket (Fox et al.)
  • Improves the self-renewal ability of neural stem cells from NPC1-deficient mice (Yang et al.)
  • Blocks adiponectin-mediated proliferation of hematopoietic stem cells (DiMascio et al.)
  • Reduces BMP3-mediated proliferation of C3H10T1/2 mesenchymal stem cells (Stewart et al.)
  • Induces cardiomyocyte differentiation from human embryonic stem cells (Graichen et al.)
Specifications

Specifications

152121-30-7
C20H14FN3O
≥98%
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