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STEMCELL Technologies SB202190

p38 MAPK inhibitor

3187.35 SEK - 6164.10 SEK

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Products 2

Product Code	Brand	Quantity	Price	Quantity & Availability
Product Code	Brand	Quantity	Price	Quantity & Availability
17100102 View Documents Promotion Details missing translation for 'viewProductCertificates'	STEMCELL Technologies 72632	10 mg	3187.35 SEK 10mg View alternative products Save Up to »	Estimated Shipment: 31-07-2024 Log in to see stock.	Please sign in to purchase this item. Need a web account? Register with us today!

17110102 View Documents Promotion Details missing translation for 'viewProductCertificates'	STEMCELL Technologies 72634	25 mg	6164.10 SEK 25mg View alternative products Save Up to »	Estimated Shipment: 31-07-2024 Log in to see stock.	Please sign in to purchase this item. Need a web account? Register with us today!

Description

SB202190 is a selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38α (SAPK2A, MAPK14) and p38β (SAPK2B, MAPK11) with IC₅₀ values of 50 and 100 nM, respectively (Davies et al.; Jiang et al.) As a pyridinyl imidazole inhibitor, SB202190 directly binds p38 MAP kinases in the ATP binding pocket (Fox et al.)
Improves the self-renewal ability of neural stem cells from NPC1-deficient mice (Yang et al.)
Blocks adiponectin-mediated proliferation of hematopoietic stem cells (DiMascio et al.)
Reduces BMP3-mediated proliferation of C3H10T1/2 mesenchymal stem cells (Stewart et al.)
Induces cardiomyocyte differentiation from human embryonic stem cells (Graichen et al.)

Specifications

Description