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SCN1A Rabbit anti-Human, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1656.73 SEK - 4721.67 SEK
Specifications
Antigen | SCN1A |
---|---|
Concentration | 0.33 mg/mL |
Applications | Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16825985
|
Proteintech
28079-1-AP-20UL |
20 μL |
1656.73 SEK
20µL |
Estimated Shipment: 24-04-2024 Log in to see stock. |
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16815985
|
Proteintech
28079-1-AP-150UL |
150 μL |
4721.67 SEK
150µL |
Estimated Shipment: 24-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Epithelial sodium channels are amiloride-sensitive members of the Degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels. Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region. There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein. ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance. ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure. ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel. Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddels syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1).Specifications
SCN1A | |
Western Blot | |
Unconjugated | |
Rabbit | |
Human, Rat | |
P04774, P35498 | |
6323, 81574 | |
SCN1A Fusion Protein Ag25942 | |
Primary | |
-20°C | |
SCN1A |
0.33 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SCN1A, SMEI | |
SCN1A | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |