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SELPLG Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 23605-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16822405

  • 1236.20 SEK / 20µL
Estimated Shipment: 08-12-2021

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Description

Description

This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
Specifications

Specifications

SELPLG
0.37 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q14242
CD162, CLA, PSGL 1, PSGL1, selectin P ligand, SELPLG
Rabbit
IgG
20 μL
-20°C
Primary
6404
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
SELPLG
Liquid
SELPLG
SELPLG Fusion Protein Ag19394
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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