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SEPT5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11631-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16828843

  • 3313.85 SEK / 150µL
Estimated Shipment: 07-12-2021

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Description

Description

This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Two transcripts of this gene, a major one of 2.2 kb and a minor one of 3.5 kb, have been observed. The 2.2 kb form results from the utilization of a non-consensus polyA signal (AACAAT). In the absence of polyadenylation from this imperfect site, the consensus polyA signal of the downstream neighboring gene (GP1BB; platelet glycoprotein Ib) is used, resulting in the 3.5 kb transcript. An alternatively spliced transcript variant with a different 5′ end has also been identified, but its full-length nature has not been completely determined.
Specifications

Specifications

SEPT5
0.2 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q99719, Q9JJM9, Q9Z2Q6
CDCREL, CDCREL 1, CDCREL1, H5, Peanut like protein 1, PNUTL1, SEPT5, septin 5, septin5
Rabbit
IgG
150 μL
-20°C
Primary
116728, 18951, 5413
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
SEPT5
Liquid
SEPT5
SEPT5 Fusion Protein Ag2205
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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