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SGC0946, MedChemExpress

Produktkod. 16499267
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Produktkod. 16499267 Leverantör Medchem Express Leverantörsnummer HY15650

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Beskrivning

MedChemExpress SGC0946 is a selective DOT1LH3K79 methyltransferase) inhibitor, with an IC50 of 0.3 nM. SGC0946 results in G1 arrest, inhibits potential of cell self-renewal and metastatic, also induces cell differentiation. SGC0946 can be used in studies of leukemia and solid tumors and also serve as a probe to further investigate the cellular mechanism of DOT1L in both normal and diseased cells.

SGC0946 is a selective DOT1LH3K79 methyltransferase) inhibitor, with an IC50 of 0.3 nM. SGC0946 results in G1 arrest, inhibits potential of cell self-renewal and metastatic, also induces cell differentiation. SGC0946 can be used in studies of leukemia and solid tumors and also serve as a probe to further investigate the cellular mechanism of DOT1L in both normal and diseased cells.

Specifikationer

Kemiskt namn eller material SGC0946
CAS 1561178-17-3
Färg Light Nude
Anteckningar om renhetsgrad Research
Molekylformel C28H40BrN7O4
Kvantitet 5 mg
Löslighetsinformation DMSO : 50 mg/mL (80.83 mM; Need ultrasonic)
LEDER NC1=NC=NC2=C1C(Br)=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CN(CCCNC(NC4=CC=C(C(C)(C)C)C=C4)=O)C(C)C)O3
Molekylvikt (g/mol) 618.57
Formel vikt 618.57
Procent renhet 98.0%
Kvalitet Research
Fysisk form Solid
För användning med (applikation) Cancer-programmed cell death
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Research purposes only

Produkttitel
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