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Shikonin, MedChemExpress

Produktkod. 16483906
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16483906 25 mg
16474897 50 mg
16459118 10 mg
16419146 100 mg
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Produktkod. 16483906 Leverantör Medchem Express Leverantörsnummer HYN0822

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Beskrivning

MedChemExpress Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM. Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway. Shikonin decreases exosome secretion through the inhibition of glycolysis. Shikonin inhibits AIM2 inflammasome activation.

Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM. Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway. Shikonin decreases exosome secretion through the inhibition of glycolysis. Shikonin inhibits AIM2 inflammasome activation.

Specifikationer

Kemiskt namn eller material Shikonin
CAS 517-89-5
Färg Dark Brown
Anteckningar om renhetsgrad Research
Molekylformel C16H16O5
Kvantitet 25 mg
Synonym C.I. 75535 Isoarnebin 4
Löslighetsinformation DMSO : 25 mg/mL (86.72 mM; ultrasonic and warming and heat to 60°C)
LEDER O=C1C([C@H](O)C/C=C(C)/C)=CC(C2=C1C(O)=CC=C2O)=O
Molekylvikt (g/mol) 288.3
Formel vikt 288.3
Procent renhet 98.09%
Kvalitet Research
Fysisk form Solid
För användning med (applikation) Cancer-Kinase/protease
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Research purposes only

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