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SHKBP1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA559773
Additional Details : Weight : 0.02000kg
Description
Immunogen sequence: PVFPVKRRNR HSLVGPQQLG GRPAPVRRSN TMPPNLGNAG LLGRMLDEKT PPSPSGQPEE PGMVRLVCGH HNWIAVAYTQ FLVCYRLKEA Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 94%.
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.Specifications
| SHKBP1 | |
| Polyclonal | |
| Unconjugated | |
| SHKBP1 | |
| B930062H15Rik; PP203; RGD1309281; Sb1; SETA binding protein 1; SETA-binding protein 1; SH3KBP1 binding protein 1; SH3KBP1-binding protein 1; Shkbp1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 92799 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry, Western Blot | |
| 0.2 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q8TBC3 | |
| SHKBP1 | |
| Recombinant protein corresponding to Human SHKBP1 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Research Use Only