Learn More
SHMT2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA554232
Additional Details : Weight : 0.02000kg
Description
Immunogen sequence: NTCPGDRSAI TPGGLRLGAP ALTSRQFRED DFRRVVDFID EGVNIGLEVK SKTAKLQDFK SFLLKDSETS QRLANLRQRV EQFARAF Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
Mammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate in the cytoplasm (cSHMT, SHMT1) and mitochondria (mSHMT, SHMT2). cSHMT preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate, and inhibits SAM synthesis.Specifications
SHMT2 | |
Polyclonal | |
Unconjugated | |
SHMT2 | |
2700043D08Rik; AA408223; AA986903; epididymis secretory sperm binding protein Li 51e; GLY A+; GLYA; glycine auxotroph A, human complement for hamster; glycine hydroxymethyltransferase; HEL-S-51e; mitochondrial serine hydroxymethyltransferase; serine aldolase; serine hydroxymethylase; serine hydroxymethyltransferase; serine hydroxymethyltransferase 2; serine hydroxymethyltransferase 2 (mitochondrial); serine hydroxymethyltransferase, mitochondrial; Serine methylase; SHMT; SHMT 2; SHMT2; threonine aldolase | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
108037, 299857, 6472 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry, Immunohistochemistry, Western Blot | |
0.2 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
P34897, Q9CZN7 | |
SHMT2 | |
Recombinant protein corresponding to Human SHMT2 | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Research Use Only