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Ambion™ Silencer™ Select Pre-Designed siRNA

Silencer™ Select Pre-Designed siRNA

Brand:  Ambion™ 4399217

Additional Details : Weight : 0.00450kg

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Product Code. 10015364

  • 3325.00 SEK / Each


Estimated Shipment
15-10-2020
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For Research Use Only. All usage must comply with product instructions.


Description

Description

The Silencer™ Select siRNAs are classic 21-mers which incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemistry. A choice of Silencer™ Select siRNAs are available—Pre-Designed or Validated. Silencer™ Select Pre-Designed siRNAs are guaranteed-to-silence based on their proven design while the Silencer™ Select Validated siRNAs are functionally tested to reduce target gene expression. Sets of Silencer™ Select siRNA Libraries are also available in tubes or plate for high throughput screening. The Silencer™ Select Positive and Negative Control RNAs should be included in every siRNA experiment.

The benefits of using Silencer™ Select siRNAs include:
  • Potent—up to 100-fold more potent than currently available siRNAs and fewer off-target effects
  • Most Specific—LNA™ chemical modifications reduce off-target effects by up to 90%
  • Reliable—demonstrated improvements in consistency and reliability of phenotypic results
  • Guaranteed—100% guaranteed to silence, the best guarantee in the industry

  • Note: Silencer™ Pre-Designed & Validated siRNAs are designed using our first-generation algorithm and DO NOT include any chemical modifications. They are recommended for completing in vitro RNAi studies that were started using Silencer™ siRNAs. For new studies we recommend Silencer Select siRNAs.

    Approximate Turnaround Times*
  • Standard purification: 4 business days
  • HPLC purification: 6 business days (20 and 40 nmol); 15 business days (250 nmol)
  • In Vivo Ready: 15 business days (250 nmol)
  • Specifications

    Specifications

    Silencer® Select siRNAs are the result of recent improvements in siRNA design combined with novel chemical modifications yielding unrivaled knockdown efficiency and specificity. Our best performing siRNA for cell culture work. Silencer® siRNAs are unmodified 21 nucleotide siRNAs that have been designed with an older, yet rigorously tested design algorithm. A lower cost alternative to Silencer® Select siRNAs, but without some of the performance enhancements.
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    For Research Use Only. Not for use in diagnostic procedures.