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SKAP2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 2G3G9, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66367-1-IG-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888175

  • 3665.00 SEK / 150µL
Estimated Shipment: 31-03-2023
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Description

Description

Fyb (Fyn binding protein) and the anchoring proteins SKAP55 and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn. SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells. SKAP55 contains an N-terminal pleckstrin homology domain and a C-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines (i.e. RKxxYxxY). SKAP55-R, similar in overall structure to SKAP55, contains a coiled-coil N-terminal domain. SKAP55 associates with SLAP-130, another component of the Fyn complex, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation. The human SKAP55 gene maps to chromosome 17q21.32 and encodes a 359 amino acid protein.
Specifications

Specifications

SKAP2
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O75563, Q3UND0, Q920G0
Skap2
SKAP2 Fusion Protein Ag3615
150 μL
Primary
Rat, Porcine, Mouse, Human
Antibody
IgG1
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
2G3G9
Unconjugated
SKAP2
PRAP, Pyk2/RAFTK associated protein, RA70, SAPS, SCAP2, SKAP 55HOM, SKAP HOM, SKAP2, SKAP55 homolog, SKAP55R
Mouse
Protein G
RUO
100625903, 155183, 54353, 8935
-20°C
Liquid
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SDS
Documents

Documents

Certificates
Special Offers

Special Offers