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SKAP2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 2G3G9, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66367-1-IG-150UL
Additional Details : Weight : 0.00010kg
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DescriptionFyb (Fyn binding protein) and the anchoring proteins SKAP55 and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn. SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells. SKAP55 contains an N-terminal pleckstrin homology domain and a C-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines (i.e. RKxxYxxY). SKAP55-R, similar in overall structure to SKAP55, contains a coiled-coil N-terminal domain. SKAP55 associates with SLAP-130, another component of the Fyn complex, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation. The human SKAP55 gene maps to chromosome 17q21.32 and encodes a 359 amino acid protein.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|O75563, Q3UND0, Q920G0|
|SKAP2 Fusion Protein Ag3615|
|Rat, Porcine, Mouse, Human|
|Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry|
|PRAP, Pyk2/RAFTK associated protein, RA70, SAPS, SCAP2, SKAP 55HOM, SKAP HOM, SKAP2, SKAP55 homolog, SKAP55R|
|100625903, 155183, 54353, 8935|