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SKF-96365 hydrochloride, MedChemExpress

Produktkod. 16485467
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16485467 5 mg
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16460896 200 mg
16459426 50 mg
16414196 100 mg
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Produktkod. 16485467 Leverantör Medchem Express Leverantörsnummer HY1000015mg

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Beskrivning

MedChemExpress SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca2+ entry (SOCE) inhibitor. SKF-96365 hydrochloride significantly inhibits hERG, hKCNQ1/hKCNE1, hKir2.1 and hKv4.3 current, and significantly prolongs the QTc interval in isolated guinea pig hearts. SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells.

SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca2+ entry (SOCE) inhibitor. SKF-96365 hydrochloride significantly inhibits hERG, hKCNQ1/hKCNE1, hKir2.1 and hKv4.3 current, and significantly prolongs the QTc interval in isolated guinea pig hearts. SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells.

Specifikationer

Kemiskt namn eller material SKF-96365 hydrochloride
CAS 130495-35-1
Färg White
Anteckningar om renhetsgrad Research
Molekylformel C22H27ClN2O3
Kvantitet 5 mg
Löslighetsinformation DMSO : 100 mg/mL (248.19 mM; Need ultrasonic) ∣H2O : 100 mg/mL (248.19 mM; Need ultrasonic)
LEDER COC1=CC=C(CCCOC(C2=CC=C(OC)C=C2)CN3C=CN=C3)C=C1.[H]Cl
Molekylvikt (g/mol) 402.91
Formel vikt 402.91
Procent renhet 99.51%
Kvalitet Research
Fysisk form Powder
För användning med (applikation) Cancer-Kinase/protease
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Research purposes only

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