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SNX15 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA530538
Additional Details : Weight : 0.01000kg
Description
Recommended positive controls: MCF-7. Predicted reactivity: Mouse (93%), Rat (92%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the sorting nexin family. Members of this family contain a phox domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 gene.Specifications
SNX15 | |
Polyclonal | |
Unconjugated | |
Snx15 | |
1500032B08Rik; clone iota unknown protein; E130013C21Rik; hCG_23393; HSAF001435; OTTHUMP00000035515; SNX15; sorting nexin 15; sorting nexin-15 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
29907 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 | |
Q9NRS6 | |
Snx15 | |
Recombinant fragment corresponding to a region within amino acids 1 and 225 of Human SNX15 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |