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Beskrivning
SOD1 (superoxide dismutase) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occurring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
Specifikationer
Specifikationer
| Antigen | SOD1 |
| Användningsområden | Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence, Immunoprecipitation, Immunocytochemistry |
| Klassificering | Polyclonal |
| Koncentration | 0.2 mg/mL |
| Konjugera | Unconjugated |
| Formulering | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gen | SOD1 |
| Genaccessionsnr. | P00441, P07632, P08228 |
| Gene Alias | ALS, ALS1, homodimer, IPOA, SOD, SOD1, Superoxide dismutase [Cu Zn] |
| Gensymboler | SOD1 |
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Produkttitel
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