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STEMCELL Technologies Sodium Butyrate
Beskrivning
- Sodium Butyrate is the sodium salt of butyric acid, a short chain fatty acid that inhibits histone deacetylases (HDACs), leading to hyperacetylation of histones
- This causes changes in chromatin structure and gene expression, resulting in many biological effects
- (Boffa et al.; Kruh)
- Promotes reprogramming of human somatic cells to induced pluripotent stem (iPS) cells using only a single factor, OCT4 (Zhu et al.)
- Supports self-renewal of mouse and human embryonic stem (ES) cells, in the absence of exogenously added growth factors (Ware et al.)
- Promotes differentiation to hepatocytes from mouse and human ES cells (Hay et al.; Zhou et al.)
- Promotes differentiation to definitive endoderm and islet-like cells from human ES cells (Jiang et al.)
- Enhances osteogenic and suppresses adipogenic differentiation from human mesenchymal cells (Chen et al.; Lee et al.)
Specifikationer
Specifikationer
| CAS | 156-54-7 |
| Synonym | Butanoic acid; Butyric acid, sodium salt |
| Kvantitet | 500 mg |
| Molekylformel | C4H7O2 · Na |
| Renhet | ≥95% |
Produkttitel
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