SOX11, Biotin, clone: SOX11-C1, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 13-9773-82
Additional Details : Weight : 0.09500kg
DescriptionDescription: The monoclonal antibody SOX11-C1 (C1) recognizes human Sox11. The transcription factor Sox11 is a member of the SOX (sex determining region Y-related HMG (High Mobility Group) Box) family of proteins. Under normal conditions Sox11 is expressed in the developing central nervous system during embryogenesis and has sequence homology to Sox4. Sox11 plays a role in neuronal maturation and epithelial-mesenchymal interactions and is required for the survival of neuronal and mesenchymal progenitor cells. Sox11 is expressed in mantle cell lymphoma (MCL) and in subsets of hairy cell leukemias, Burkitt lymphomas, and B cell lymphoblastic leukemias, but is not expressed in other B cell lymphomas or in normal B lymphocytes. Sox11 is also expressed in epithelial ovarian cancer and gliomas.Applications Reported: This SOX11-C1 antibody has been reported for use in immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.Applications Tested: This SOX11-C1 antibody has been tested by immunohistochemistry on formalin-fixed paraffin embedded tissue using high pH antigen retrieval and can be used at less than or equal to 10 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|SRY (sex-determining region Y)-box 11, SRY-related HMG-box gene 11, transcription factor SOX-11|
|IgG1, kappa, kappa|
|Store at 2-8°C. Do not freeze.|
For Research Use Only.