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SPAG6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 12462-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16850184

  • 1656.73 SEK / 20µL
Estimated Shipment: 02-04-2024
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Description

Description

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintece of the structural integrity of mature sperm. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.
Specifications

Specifications

SPAG6
Polyclonal
Unconjugated
SPAG6
pf16, Protein PF16 homolog, Repro SA 1, SPAG6, sperm associated antigen 6, Sperm flagellar protein
Rabbit
Antigen Affinity Chromatography
RUO
360747, 381350, 9576
-20°C
Liquid
Immunoprecipitation, Western Blot
0.13 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O75602, Q9JLI7
Spag6
SPAG6 Fusion Protein Ag3130
20 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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