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SPDYA Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 17836-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16827834

  • 3313.85 SEK / 150µL
Estimated Shipment: 08-12-2021

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Description

Description

Speedy A, also known as SPDYA, SPDY1, Ringo3 or SPY1, is a 313 amino acid protein that localizes to the nucleus and belongs to the speedy/ringo family. Expressed at high levels in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver spleen and placenta, Speedy A functions to regulate the G1/S phase transition of the cell cycle, specifically by binding to and activating Cdc2 p34, Cdk2 and p27. Additionally, Speedy A mediates cell survival during DNA damage, suggesting that Speedy A plays a role in proper cell cycle progression throughout the life of the cell. Multiple isoforms of Speedy A exist due to alternative splicing events. The gene encoding Speedy A maps to human chromosome 2, which encodes over 1,400 genes and comprises nearly 8% of the human genome.
Specifications

Specifications

SPDYA
0.29 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q5IBH7, Q5MJ70, Q8R496
hSpy/Ringo A, RINGO A, Ringo3, SPDY1, SPDYA, Speedy 1, Speedy protein A, SPY1
Rabbit
IgG
150 μL
-20°C
Primary
192209, 245711, 70891
Immunoprecipitation, Western Blot
Unconjugated
SPDYA
Liquid
Spdya
SPDYA Fusion Protein Ag12041
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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