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SPP Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 20416-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16839954

  • 1236.20 SEK / 20µL
Estimated Shipment: 03-10-2022
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Description

Description

Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides. May play a role in graft rejection. May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein. Involved in the intramembrane cleavage of the integral membrane protein PSEN1. Cleaves the integral membrane protein XBP1 isoform 1 in a DERL1/RNF139- dependent manner.
Specifications

Specifications

SPP
Polyclonal
Unconjugated
HM13
H13, hIMP1, histocompatibility (minor) 13, HM13, IMP 1, IMP1, IMPAS, IMPAS 1, Intramembrane protease 1, MSTP086, Presenilin like protein 3, PSENL3, PSL3, Signal peptide peptidase, SPP
Rabbit
Antigen Affinity Chromatography
RUO
14950, 81502
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q8TCT9, Q9D8V0
Hm13
SPP Fusion Protein Ag14158
20 μL
Primary
Human, Mouse
Antibody
IgG
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