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Invitrogen™ SSEA5 Monoclonal Antibody (8E11)
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Produktkod. 15316281
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Kvantitet:
100 μg
Förpackningsstorlek:
100µg
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15316281 100 μg 100µg
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Produktkod. 15316281 Leverantör Invitrogen™ Leverantörsnummer MA1144

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Mouse Monoclonal Antibody

Immunofluorescence and flow cytometric analysis of MA1-144 shows positive staining of SSEA-5 positive pluripotent cells within cultured human embryonal carcinoma NCCIT and NTERA-2 cells. Mouse teratocarcinoma cell line F9 was used as a negative control and showed no staining.

Stage-Specific Embryonic Antigen-5 (SSEA-5) is an oligosaccharide that can be part of glycosphingolipids and glycoproteins. It contains the motif Fuc1-2Gal-beta1-3GlcNAc-beta, which is characteristic of H-1 antigens. SSEA-5 is found in the inner cell mass of the human blastocyst during embryogenesis, on undifferentiated human embryonic stem cells and on the surface of induced pluripotent cells. SSEA-5 was found to proceed the loss of other known stem cell markers and the combination of SSEA-5 with either CD9 and CD90 or CD50 and CD200 was superior in identifying and eliminating rare undifferentiated human ES cells from differentiated cell populations than the use of other established stem cell markers.
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Specifikationer

Antigen SSEA5
Användningsområden Flow Cytometry, Immunocytochemistry
Klassificering Monoclonal
Klona 8E11
Koncentration 1 mg/mL
Konjugera Unconjugated
Formulering PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Alias SSEA-5
Värd art Mouse
Immunogen Undifferentiated H9 human embryonic stem cells.
Reningsmetod Protein A
Kvantitet 100 μg
Regulatorisk status RUO
Primär eller sekundär Primary
Målarter Human
Innehåll och lagring -20°C
Produkttyp Antibody
Form Liquid
Isotyp IgG1 κ
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