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STAT5B Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 51072-2-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16826365

  • 3248.87 SEK / 150µL
Estimated Shipment: 30-11-2021

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Description

Description

This antibody is specific to STAT5B. It has no cross reaction to STAT5A.

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
Specifications

Specifications

STAT5B
0.15 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P51692
STAT5, STAT5B, STAT5B-Specific
Rabbit
IgG
150 μL
-20°C
Primary
6777
Western Blot
Unconjugated
STAT5B
Liquid
STAT5B
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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