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STMN4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 12027-1-AP-20UL
Additional Details : Weight : 0.00010kg
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DescriptionRB3 (Stathmin-4), encoded by STMN4 gene, is a neuron-specific homologue of the SCG10/stathmin family proteins, possessing a unique N-terminal membrane-associated domain and the stathmin-like domain at the C terminus, which promotes microtubule (MT) catastrophe and/or tubulin sequestering. Stathmin is a ubiquitous cytosolic phosphoprotein, preferentially expressed in the nervous system, and described as a relay integrating diverse intracellular signaling pathways. RB3 is consistently up-regulated in differentiated neuroblastoma cells, and stable expression of transfected RB3 could induce differentiation, suggesting a role of RB3 during neuroblastoma differentiation. Moreover, increased RB3 is a unique response protein in the stathmin-related proteins following optical nerve axotomy and RB3 may be a critical target for neurodegenerative diseases.
|RB3, Stathmin 4, stathmin like 4, Stathmin like protein B3, STMN4|
|Antigen Affinity Chromatography|
|56471, 79423, 81551|
|Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation|
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|P63042, P63043, Q9H169|
|STMN4 Fusion Protein Ag2657|
|Mouse, Rat, Human|