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STRO-1, clone: STRO-1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-6688-82

Additional Details : Weight : 0.09500kg

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Product Code. 15507476

  • 2595.00 SEK / 100µg


Estimated Shipment date
from Supplier 24-04-2019
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Description

Description

2 µm post-manufacturing filtered. STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow. STRO-1 binds to approximately 10% of bone marrow mononuclear cells, greater than 95% of which are nucleated erythroid precursors, but does not react with committed progenitor cells (colony-forming unit granulocyte-macrophage (CFU-GM), erythroid bursts (BFU-E), and mixed colonies (CFU-Mix). From bone marrow cells, the frequency of fibroblast colonyforming cells (CFU-F) is enriched approximately 100-fold in the STRO-1-positive/Glycophorin A-negative population than in the STRO-1-positive/Glycophorin A-positive population. When plated under long-term BM culture conditions, STRO-1-positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, and fibroblastic elements. A STRO-1-positive enriched subset of marrow cells is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts and chondrocytes. STRO-1 is a valuable antibody for the identification, isolation and functional characterization of human bone marrow stromal cell precursors.
Specifications

Specifications

Stro-1
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
STRO1
IgM, lambda
100 μg
4° C
Primary
Bovine, Human, Rat
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
STRO-1
Unconjugated
Liquid
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
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