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Survivin Monoclonal Antibody (STLALYV), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
2120.00 SEK - 4650.00 SEK
Specifications
Antigen | Survivin |
---|---|
Clone | STLALYV |
Classification | Monoclonal |
Conjugate | Alexa Fluor 488 |
Form | Liquid |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15560267
|
Affymetrix eBioscience
53-9176-82 |
100 μg |
4650.00 SEK
100µg |
Estimated Shipment: 07-05-2024 Log in to see stock. |
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15550267
|
Affymetrix eBioscience
53-9176-80 |
25 μg |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: This STLALYV monoclonal antibody recognizes human survivin (also known as Birc5). Survivin is a member of the inhibitor of apoptosis (IAP) family that also includes XIAP, c-IAP1, c-IAP2, and NAIP. Survivin functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis. Survivin also plays a critical role in mitosis and cytokinesis where it is expressed only during G2/M and localizes to the mitotic spindle and is found at the cleavage furrow/midplate. Thus, survivin is highly expressed in tumors and in fetal tissue, but is absent in terminally-differentiated cells and non-proliferating cells. Deletion of survivin in developing thymocytes as well as in mature T cells showed that survivin is critical for cell division in lymphoid cells but not for inhibition of survival; the same is true for B lymphocytes. Applications Reported: This STLALYV antibody has been reported for use in microscopy, and immunocytochemistry. Applications Tested: This STLALYV antibody has been tested by immunocytochemistry of fixed and permeabilized cells and can be used at less than or equal to 10 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered.
Survivin Monoclonal antibody specifically detects Survivin in Human samples. It is validated for Immunocytochemistry, Immunohistochemistry.Specifications
Survivin | |
Monoclonal | |
Liquid | |
RUO | |
O15392 | |
IgG2b κ | |
Affinity chromatography |
STLALYV | |
Alexa Fluor 488 | |
Mouse | |
Human | |
332 | |
Primary | |
Antibody |
For Research Use Only.