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TACC3 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 25697-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16824265

  • 1236.20 SEK / 20µL
Estimated Shipment: 02-12-2021

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Description

Description

This antibody works well in WB, IHC and IF application.

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
Specifications

Specifications

TACC3
0.27 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9Y6A5
ERIC 1, ERIC1, TACC3
Rabbit
IgG
20 μL
-20°C
Primary
10460
Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence, Immunocytochemistry
Unconjugated
TACC3
Liquid
TACC3
TACC3 Fusion Protein Ag22516
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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