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TAK-220, MedChemExpress

Produktkod. 16473917
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16473917 50 mg
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16417776 100 mg
16407998 10 mg
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Produktkod. 16473917 Leverantör Medchem Express Leverantörsnummer HY19974

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Beskrivning

MedChemExpress TAK-220 is a selective and orally bioavailable CCR5 antagonist, with IC50s of 3.5 nM and 1.4 nM for inhibition on the binding of RANTES and MIP-1α to CCR5, respectively, but shows no effect on the binding to CCR1, CCR2b, CCR3, CCR4, or CCR7

TAK-220 also selectively inhibits HIV-1, with EC50s of 1.2 nM (HIV-1 KK), 0.72 nM (HIV-1 CTV), 1.7 nM (HIV-1 HKW), 1.7 nM (HIV-1 HNK), 0.93 nM (HIV-1

Specifikationer

Kemiskt namn eller material TAK-220
CAS 333994-00-6
Färg Off-White
Anteckningar om renhetsgrad Research
Molekylformel C31H41ClN4O3
Kvantitet 50 mg
Löslighetsinformation DMSO : ≥ 50 mg/mL (90.39 mM)
LEDER O=C(C1CCN(C(C)=O)CC1)N(CCCN2CCC(CC3=CC=C(C(N)=O)C=C3)CC2)C4=CC=C(C)C(Cl)=C4
Molekylvikt (g/mol) 553.14
Formel vikt 553.14
Procent renhet 99.9%
Kvalitet Research
Fysisk form Solid
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Research purposes only

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