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TALPID3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 24421-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16882895

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

KIAA0586 also named as Talpid3 is a 1472 amino-acid protein, which belongs to Talpid3 family. Talpid3 is a gene essential for vertebrate development. Studies in chicken, mouse, zebrafish and human have shown that TALPID3 is a centrosomal protein, mutants null for TALPID3 fail to produce cilia, resulting in far reaching signaling defects such as polydactyly, dorsalised neural tube, craniofacial and vascular defects often due to abnormalities in Hedgehog signal transduction. Talpid3 is absolutely required for the function of both Gli repressor and activator in the intracellular Hedgehog pathway and ciliogenesis. TALPID3 may be identified as a subcellular maker of centrosome and needed to further studied.
Specifications

Specifications

TALPID3
0.41 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9BVV6
KIAA0586, KIAA0586 isoform, Talpid3
Rabbit
IgG
20 μL
-20°C
Primary
9786
Immunohistochemistry (Paraffin)
Unconjugated
KIAA0586
Liquid
KIAA0586
TALPID3 Fusion Protein Ag19813
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Human
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