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TBC1D17 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA564361
Additional Details : Weight : 0.02000kg
Description
Immunogen sequence: GVYLHTSAKK YQDRDSLIAG VIRVVEKDND VLLHWAPVEE AGDSTQILFS KKDSSGGDSC ASEEEPTFDP GYEPDWAVIS TVRPQLCHSE PTRGAEPSC Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 82%.
Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known. [UniProt]Specifications
| TBC1D17 | |
| Polyclonal | |
| Unconjugated | |
| TBC1D17 | |
| BC017607; hypothetical protein LOC554092; TBC1 domain family member 17; TBC1 domain family, member 17; TBC1D17; wu:fc56c02; zgc:110443; zgc:110443 protein | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 79735 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry | |
| 0.2 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9HA65 | |
| TBC1D17 | |
| Recombinant protein corresponding to Human TBC1D17 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Research Use Only