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TBL3 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA560024
Additional Details : Weight : 0.02000kg
Description
Immunogen sequence: LWKDVTEAEQ AEEQARQEEQ VVRQQELDNL LHEKRYLRAL GLAISLDRPH TVLTVIQAIR RDPEACEKLE ATMLRLRRDQ KEALLRFCVT WNTNSRHCHE AQAVLGVLL Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.
WNK is a serine/threonine kinase that plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, and SGK1. WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron. Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy.Specifications
| TBL3 | |
| Polyclonal | |
| Unconjugated | |
| TBL3 | |
| 9430070M15Rik; SAZD; Tbl3; transducin (beta)-like 3; transducin beta like 3; transducin beta-like 3; transducin beta-like protein 3; UTP13; WD repeat-containing protein SAZD; WD-repeat protein SAZD | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 10607 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q12788 | |
| TBL3 | |
| Recombinant protein corresponding to Human TBL3 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Research Use Only