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TDP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10641-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16887143

  • 3313.85 SEK / 150µL
Estimated Shipment: 08-12-2021

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Description

Description

The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.
Specifications

Specifications

TDP1
0.13 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q4G056, Q8BJ37, Q9NUW8
TDP1, Tyr DNA phosphodiesterase 1
Rabbit
IgG
150 μL
-20°C
Primary
104884, 314380, 55775
Immunoprecipitation, Western Blot
Unconjugated
TDP1
Liquid
Tdp1
TDP1 Fusion Protein Ag0964
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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