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Invitrogen™ TGF alpha Monoclonal Antibody (D20), Invitrogen™
Beskrivning
TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Tekniske data
Tekniske data
| Antigen | TGF alpha |
| Användningsområden | Immunohistochemistry (Paraffin), Western Blot |
| Klassificering | Monoclonal |
| Klona | D20 |
| Koncentration | 1 mg/mL |
| Konjugera | Unconjugated |
| Formulering | PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 |
| Gen | TGFA |
| Genaccessionsnr. | P01134, P01135 |
| Gene Alias | EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF α; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFα; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1 |
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Produkttitel
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