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Invitrogen™ TGF alpha Recombinant Mouse Monoclonal Antibody (tAb2)
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Produktkod. 30089201
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Kvantitet:
200 μg
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Produktkod. Kvantitet
30089201 200 μg
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Produktkod. 30089201 Leverantör Invitrogen™ Leverantörsnummer MA551826

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Mouse Recombinant Monoclonal Antibody

tAb2 binds the N-terminal sequence of transforming growth factor alpha, VVSHFND (with residues 4 to 7 being the minimal binding epitope).

TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen TGF alpha
Användningsområden Dot Blot, ELISA, In vitro Assay
Klassificering Recombinant Monoclonal
Klona tAb2
Koncentration 1 mg/mL
Konjugera Unconjugated
Formulering PBS with 0.02% ProClin 300
Gen TGFA
Genaccessionsnr. P01135
Gene Alias EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF α; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFα; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1
Gensymboler TGFA
Värd art Mouse
Immunogen Biologically active hemocyanin-coupled human TGFalpha (N-terminal).
Reningsmetod Protein A
Kvantitet 200 μg
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 7039
Målarter Human
Innehåll och lagring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Liquid
Isotyp IgG2a κ
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Produkttitel
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