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Invitrogen™ Human CRP, Recombinant Protein

Recombinant Protein

Brand:  Invitrogen™ RP75527

Additional Details : CAS Number : 69-74-9 Weight : 0.01000kg

Product Code. 11514221

  • 2080.00 SEK / 10µg
Estimated Shipment: 02-06-2022
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Description

Description

C-Reactive Protein (human) Recombinant Protein, RP-75527, from Invitrogen.

CRP (C-reactive protein) is a major cyclic, pentameric acute phase protein compound consisting of five identical, noncovalently bound, nonglycosylated subunits. Eeach subunit is made up of 206 amino acids, and has a molecular weight of 24 kDa. CRP is produced by the liver, and its plasma levels rise dramatically during inflammatory processes occurring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.), plays an important role in innate immunity, and mediates activities associated with pre-immune nonspecific host resistance. Specifically, there is a 100-1000 fold increase of CRP in response to injury, infection or inflammation. CRP is opsonic, an initiator of the classical complement cascade, and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. CRP is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host, and initiates pathogen elimination by interacting with humoral and cellular effector systems in the blood. Patients with elevated basal levels of CRP have been shown to be an increased risk for hypertension and cardiovascular disease. RP-75527 contains purified recombinant human C-Reactive Protein protein. RP-75527 may be used as a positive control in many immunological assays.
Specifications

Specifications

P02741
Liquid
1401
7.5
10μg
N/A
RUO
CRP
Unlabeled
E. coli
Recombinant
Control, Western Blot
20mM tris HCl with 0.14M NaCl, 2mM CaCl2 and 0.05% sodium azide; pH 7.5
Human CRP
purified
E. coli
4°C
Human CRP
Human
Hu
Recombinant
Control, Western Blot
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