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Invitrogen™ Human Diazepam Binding Inhibitor, Recombinant Protein
Recombinant Protein
Brand: Invitrogen™ LFP0046
Additional Details : Weight : 0.99000kg
Description
Diazepam Binding Inhibitor Recombinant Protein, LF-P0046, from Invitrogen.
Diazepam Binding Inhibitor (DBI) is a highly conserved 10 kDa polypeptide which is expressed in various species range from yeast to mammals. As an inverse agonist for benzodiazepine receptors, DBI downregulates inhibitory effects of GABA. It also has potential to induce anxiety. Found in central and peripheral tissues, DBI also participates in metabolism of steroids, which has been known to partially modify GABAA receptor function in the CNS. In peripheral tissues, DBI plays regulatory roles in steroidogenesis. DBI levels have been reported to be decreased in the cerebrospinal fluid obtained from patients with Alzheimer′s disease. This protein corresponds to human DBI (1-87 aa with N-GST tag), which has a molecular weight of 38 kDa. Purity: >95% by SDS-PAGE. After reconstitution, store at -80°C and avoid freeze and thaw cycles.Specifications
P07108 | |
0.02M HEPES with no preservative; pH 7.4 | |
Human Diazepam Binding Inhibitor | |
500μg | |
-20°C | |
Human Diazepam Binding Inhibitor | |
Human | |
Hu | |
Recombinant | |
Recombinant |
Control | |
1622 | |
7.4 | |
E. coli | |
RUO | |
DBI | |
Unconjugated | |
E. coli | |
Lyophilized | |
purified |