missing translation for 'onlineSavingsMsg'
Learn More

Human NSE, Recombinant Protein, Invitrogen™

Recombinant Protein

Brand:  Invitrogen RP75668

Additional Details : CAS Number : 69-74-9 Weight : 0.01000kg

Product Code. 11528991

  • 1740.00 SEK / 10µg
Estimated Shipment: 11-02-2022

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Neuron Specific Enolase (human) Recombinant Protein, RP-75668, from Invitrogen.

Neuron specific enolase (NSE, ENO1, ENO2, ENO3) is an enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in the glycolytic pathway, and the reverse reaction in gluconeogenesis. NSE has a high stability in biological fluids and can easily diffuse to the extracellular medium and cerebrospinal fluid (CSF) when neuronal membranes are injured. NSE is one of three mammalian enolases, which are also known as ENO1, ENO2, and ENO3 or alternately as enolase alpha, beta and gamma. The alpha-subunit is expressed in most tissues, the beta-subunit only in muscle, and the gamma-subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. Co-expression of NSE and chromogranin A is common in neuroendocrine neoplasms. Since neurons require a great deal of energy, they are very rich in glycolytic enzymes such a GAPDH and NSE. Antibodies to NSE protein are useful to identify neuronal cell bodies, developing neuronal lineage and neuroendocrine cells. Release of NSE from damaged neurons into CSF and blood has also been used as a biomarker of neuronal injury. NSE is used clinically as a sensitive and useful marker of neuronal damage in several neurological disorders including stroke, hypoxic brain damage, status epilepticus, Creutzfeldt-Jakob disease, and herpetic encephalitis. Further, NSE is found in elevated concentrations in plasma and certain neoplasias that include pediatric neuroblastoma and small cell lung cancer. This product contains purified recombinant human Neuron Specific enolase protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.
Specifications

Specifications

P09104
Control, Western Blot
Liquid
2026
purified
E. coli
-20°C, Avoid Freeze/Thaw Cycles
Neuronal Specific Enolase, NSE
ENO2
Unlabeled
E. coli
Recombinant
Control, Western Blot
PBS with 50% glycerol and no preservative
Human NSE
10μg
N/A
RUO
Human NSE
Human
Hu
Recombinant
Videos
SDS
Documents
Certificates
Special Offers

Special Offers