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Invitrogen™ Mouse IL-2 Recombinant Protein
Recombinant Protein
Brand: Invitrogen™ RP8605
Additional Details : Weight : 0.01000kg
Description
IL-2 (mouse) Recombinant Protein, RP-8605, from Invitrogen.
Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli. Recombinant mouse IL-4 is a non-glycosylated protein, containing 121 amino acids, with a molecular weight of 13.5 kDa. Purity is typically greater than 98% and endotoxin level less than 1 EU/ug. The expected biological activity (ED50) is determined by the dose-dependent induction of HT-2 cell proliferation and is typically less than 2ng/mL. The specific activity of this protein is 5x10^5 units/mg. Reconstitute using sterile water at 0.1mg/mL and centrifuge prior to opening vial. Gently pipet solution down the sides of the vial. DO NOT VORTEX sample. Store reconstituted material at -20°C and add 0.1% BSA for additional stability. Amino acid sequence: MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S.Specifications
P04351 | |
Control | |
16183 | |
4.0 | |
E. Coli | |
RUO | |
Mouse IL-2 | |
Mouse | |
Ms | |
Recombinant | |
Recombinant |
0.1mg/mL | |
0.01M citric acid, water with no preservative; pH 4.0 | |
Mouse IL-2 | |
20μg | |
-20°C, Avoid Freeze/Thaw Cycles | |
M-IL-2 | |
Il2 | |
Unconjugated | |
E. coli | |
Lyophilized | |
Size-exclusion - Dialysis |