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Thiamphenicol

Produktkod. 15495769
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Produktkod. 15495769 Leverantör Thermo Scientific Alfa Aesar Leverantörsnummer J63575.06
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Beskrivning

The methyl-sulfonyl analogue of chloramphenicol | CAS: 15318-45-3 | C12H15Cl2NO5S | 356.214 g/mol

Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

Solubility
Soluble in acetonitrile or DMF. Slightly soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
TRUSTED_SUSTAINABILITY

Kemiska identifierare

CAS 15318-45-3
Molekylformel C12H15Cl2NO5S
Molekylvikt (g/mol) 356.214
MDL-nummer MFCD00467983
InChI-nyckel OTVAEFIXJLOWRX-NXEZZACHSA-N
Synonym thiamphenicol, thiophenicol, thiamcol, +-thiamphenicol, raceophenidol, thiocymetin, dextrosulphenidol, thiamphenicolum, d-thiocymetin, d-thiophenicol
PubChem CID 27200
ChEBI CHEBI:32215
IUPAC-namn 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
LEDER CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O

Specifikationer

Kemiskt namn eller material Thiamphenicol
Färg White to Yellow
Kvantitet 5 g
Beilstein 2819542
Merck Index 14,9301
Löslighetsinformation Soluble in acetonitrile or DMF; Slightly soluble in water
Formel vikt 356.22
Fysisk form Powder

RUO – Research Use Only

Produkttitel
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