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TIGIT Mouse anti-Human, FITC, Clone: MBSA43, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-9500-41

Additional Details : Weight : 0.23750kg

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Product Code. 15516626

  • 1265.00 SEK / 25 tests


Estimated Shipment date
from Supplier 27-09-2017
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Disclaimers:

For Research Use Only.


Description

Description

The MBSA43 monoclonal antibody reacts with human T cell immunoreceptor with Ig and ITIM domains (TIGIT), which is also known as VSTM3 or WUCAM. This 26kDa protein is a member of the poliovirus receptor (PVR) family. The expression of TIGIT has been reported on NK cells, regulatory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells, but it is not expressed on B cells or naïve CD4+ T cells. TIGIT may be upregulated on naïve CD4+ T cells upon activation. TIGIT can interact with certain members of the PVR and PVR-like families, including CD155, and also mediates the interaction of NK and T cells with antigen presenting cells, fibroblasts, and endothelial cells that express PVR and PVR-like proteins.

MBSA43 is reported to crossreact with Rhesus macaque.
Specifications

Specifications

TIGIT
MBSA43
FITC
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
VSTM3, WUCAM
IgG1
RUO
Primary
Human