TNF alpha, clone: MAb11, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-7349-85
Additional Details : Weight : 0.01000kg
DescriptionDescription: The MAb11 antibody reacts with human tumor necrosis factor-alpha (TNF alpha), a 17kDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4+ T cells. TN alpha has cytolytic activity against a range of tumor cells and is important in immune regulation. TNF alpha forms dimers and trimers and also exists as a 26kDa membrane bound form. The MAb11 antibody is a neutralizing antibody.Applications Reported: MAb11 has been reported for use in detection of human TNF alpha by ELISA. It can also be used for intracellular flow cytometric analysis.Applications Tested: The biotinylated format for this lot of MAb11 has been tested by sandwich ELISA for the detection of human TNF alpha in combination with MAb1 and can be used at 1 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.09% sodium azide; pH 7.2|
|DADB-70P7.1, DIF, TNF-alpha, TNFA, TNFSF2|
|IgG1, kappa, kappa|
For Research Use Only.