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Thermo Scientific™ Tobramycin, 97%

Tobramycin, CAS# 32986-56-4, is an aminoglycoside antibiotic isolated from Streptomyces tenebrarius with a wide range of bacteriostatic activity, mainly against gram-negative bacteria.

489.37 SEK - 4672.06 SEK

Chemical Identifiers

CAS 32986-56-4
Molecular Formula C18H37N5O9
Molecular Weight (g/mol) 467.52
InChI Key NLVFBUXFDBBNBW-PBSUHMDJSA-N
PubChem CID 36294
ChEBI CHEBI:28864
IUPAC Name (2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol
SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(CC(C(O3)CN)O)N)N
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15512610
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Thermo Scientific™
455430010
1g
489.37 SEK
1g
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455430050
5g
1223.37 SEK
5g
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Thermo Scientific™
455430250
25g
4672.06 SEK
25g
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Description

Description

This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Information

• Tobramycin is an aminoglycoside compound derived from kanamycin B and displays antibiotic and bacteriostatic activity against gram-negative bacteria
• After entering the cells, it binds irreversibly to a specific aminoglycoside receptor on the bacterial 30S ribosomal subunit and interferes with the initiation complex between messenger RNA and the 30S subunit, consequently inhibiting the protein synthesis process leading to bacterial cell death
• Tobramycin also can interfere with protein elongation since it can induce misreading of the mRNA template, and cause incorrect amino acids to be incorporated into the growing polypeptide chain

Applications

• Due to its activity, tobramycin has been widely applied as a antibiotic
• It has been used to treat pseudomonas aeruginosa infections and is also being investigated for the treatment of sinus infections in vivo animal models
• Tobramycin has been used to study the effect of tobramycin on bacteriophage infected biofilms

Specifications

Chemical Identifiers

32986-56-4
467.52
36294
(2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol
C18H37N5O9
NLVFBUXFDBBNBW-PBSUHMDJSA-N
CHEBI:28864
C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(CC(C(O3)CN)O)N)N

Specifications

Tobramycin
Authentic
Solubility in water: soluble in cold water.
C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(CC(C(O3)CN)O)N)N
467.52
Solubility in water: soluble in cold water.
467.51
8% max.
32986-56-4
C18H37N5O9
NLVFBUXFDBBNBW-PBSUHMDJSA-N
(2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol
36294
CHEBI:28864
97%
1g
Safety and Handling

Safety and Handling

Product Identifier
  • Tobramycin

Signal Word
  • Warning

Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3

Hazard Statement
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
  • H315-Causes skin irritation.

Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

SDS
Product Certifications

RUO – Research Use Only