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Tolbutamide, 98%

Produktkod. 11460287
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Produktkod. 11460287 Leverantör Thermo Scientific Alfa Aesar Leverantörsnummer B21698.09
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Beskrivning

CAS: 64-77-7 | C12H18N2O3S | 270.347 g/mol

Tolbutamide, have been used in a cDNA microarray assay to probe changes in gene expression in HepG2 cells upon their administration. It has been utilized to counteract insulin activity in a patch-clamp investigation of ATP sensitive K+ channels in mouse pancreatic β-cells. The activity of various biotransformation enzymes in cultured primary rat proximal tubular cells in the presence of tolbutamide and other compounds has been studied.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tolbutamide, have been used in a cDNA microarray assay to probe changes in gene expression in HepG2 cells upon their administration. It has been utilized to counteract insulin activity in a patch-clamp investigation of ATP sensitive K+ channels in mouse pancreatic β-cells. The activity of various biotransformation enzymes in cultured primary rat proximal tubular cells in the presence of tolbutamide and other compounds has been studied.

Solubility
Soluble in chloroform.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
TRUSTED_SUSTAINABILITY

Kemiska identifierare

CAS 64-77-7
Molekylformel C12H18N2O3S
Molekylvikt (g/mol) 270.347
MDL-nummer MFCD00027169
InChI-nyckel JLRGJRBPOGGCBT-UHFFFAOYSA-N
Synonym tolbutamide, orinase, 1-butyl-3-tosylurea, tolbutamid, aglicid, arkozal, artosin, diabetol, dolipol, rastinon
PubChem CID 5505
ChEBI CHEBI:27999
IUPAC-namn 1-butyl-3-(4-methylphenyl)sulfonylurea
LEDER CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C

Specifikationer

Kemiskt namn eller material Tolbutamide
Smältpunkt 128°C to 130°C
Kvantitet 10 g
Beilstein 1984428
Merck Index 14,9507
Löslighetsinformation Soluble in chloroform.
Formel vikt 270.35
Procent renhet 98%

Säkerhet och hantering

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Produktbeteckning
  • Tolbutamide
 Signalord
  • Varning
 Riskkategorier
  • Akut toxicitet Kategorija 4
  • Preobcutljivost koze Kategorija 1
 Faroangivelser
  • H302-Skadligt vid förtäring.
  • H317-Kan orsaka allergisk hudreaktion.
 Skyddsangivelse
  • P280-Använd skyddshandskar/skyddskläder/ögonskydd/ansiktsskydd.
  • P301+P330+P331-VID FÖRTÄRING: Skölj munnen. Framkalla INTE kräkning.
  • P302+P352-VID HUDKONTAKT: Tvätta med mycket vatten/.
  • P312-Vid obehag, kontakta GIFTINFORMATIONSCENTRALEN/läkare/ .
  • P333+P313-Vid hudirritation eller utslag: Sök läkarhjälp.
 Kompletterande information
  • MIXTURE LIST-Contain: Tolbutamide

RUO – Research Use Only

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