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TOX Rat anti-Human, Mouse, Clone: TXRX10, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-6502-80

Additional Details : Weight : 0.01000kg

Product Code. 15237717

  • 924.00 SEK / 25µg


Estimated Shipment date
from Supplier 29-03-2019
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Description

Description

TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development. It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.
Specifications

Specifications

TOX
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
O94900, Q66JW3
TOX1, thymocyte selection-associated high mobility group box protein TOX, thymus high mobility group box protein TOX
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Mouse
Immunoprecipitation, Western Blot
TXRX10
Unconjugated
TOX
Liquid
TOX
IgG2a, kappa
25 μg
4° C
Primary
252838, 9760
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