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TOX Rat anti-Human, Mouse, eFluor® 660, Clone: TXRX10, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-6502-80

Additional Details : Weight : 0.09500kg

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Product Code. 15500007

  • 1290.00 SEK / 25µg


Estimated Shipment date
from Supplier 22-07-2019
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Description

Description

Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. eFluor® 660 is a replacement for Alexa Fluor® 647. eFluor® 660 emits at 659 nm and is excited with the red laser (633 nm). Please make sure that your instrument is capable of detecting this fluorochome. Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered. TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development. It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.
Specifications

Specifications

TOX
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
O94900, Q66JW3
TOX1, thymocyte selection-associated high mobility group box protein TOX, thymus high mobility group box protein TOX
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Mouse
Flow Cytometry
TXRX10
eFluor® 660
TOX
Liquid
TOX
IgG2a, kappa
25 μg
4° C, store in dark, DO NOT FREEZE!
Primary
252838, 9760
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